Staphylococcal scalded skin syndrome
☆ گېرمانىيەدىن كەلگەن 2022-يىلدىكى Stiftung Warentest نەتىجىسىدە ، ئىستېمالچىلارنىڭ ModelDerm غا بولغان رازىمەنلىكى ھەقلىق يىراقتىن داۋالاش مەسلىھەتچىلىكىدىن سەل تۆۋەن بولدى.
Staphylococcal scalded skin syndrome بار بوۋاق
References
Staphylococcal Scalded Skin Syndrome مەلۇم خىل ستافىلوككوك باكتېرىيەسى كەلتۈرۈپ چىقارغان زەھەرلىك ماددىلار سەۋەبىدىن تېرە تۆكۈلىدىغان ئەھۋال. ئالتە ياشتىن ئاشقان بالىلاردا ئاز ئۇچرايدۇ. ئىممۇنىتېت كۈچى ئاجىز ياكى بۆرەك مەسىلىسى ئېغىر قۇرامىغا يەتكەنلەردىمۇ كۆرۈلىدۇ. ئاساسلىق ئالاھىدىلىكى ياللۇغلانغاندىن كېيىنكى كەڭ تېرە پوستى. ئېغىرلىق بىر نەچچە قاپارتقۇدىن تارتىپ تېرىنىڭ كەڭ كۆلەمدە يوقىلىشىغىچە بولىدۇ ، بۇ بەدەن تېمپېراتۇرىسىنىڭ ئېغىر تۆۋەنلىشىنى ۋە قان بېسىمنىڭ تۇراقسىزلىقىنى كەلتۈرۈپ چىقىرىدۇ.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
10 ئايلىق بولغان بالا بۇرنىدىن ئېقىپ كىرىپ ياخشى تاماق يېمىدى. دوختۇرلار بۇنىڭ يۇقىرى نەپەس يولى يۇقۇملىنىش ئىكەنلىكىنى ئېيتتى. ئىككى كۈندىن كېيىن ، ئۇ ياخشى بولۇپ كەتمىگەچكە ، چىرايى ئىششىپ ، ئېغىز ئەتراپىدا تېرە غىدىقلىنىش قاتارلىق يېڭى مەسىلىلەرگە دۇچ كەلگەنلىكى ئۈچۈن قايتىپ كەلدى. كېيىنكى ئىككى كۈندە ، بالا تېخىمۇ ناچارلاشتى. ئۇنىڭ قول-پۇتلىرى ئىششىپ ، تېرىسى چىقىشقا باشلىدى. دوختۇرخانىغا قايتىپ كەلگەندىن كېيىن ، دوختۇرلار ئۇنىڭ يۈزى ۋە تېرىسىنىڭ قاتلىمىدا قىزىل داغ بارلىقىنى بايقىدى. ئۇلار ئۇنىڭغا staphylococcal scalded skin syndrome (SSSS) دەپ دىئاگنوز قويدى ۋە ئۇنى تومۇر ئارقىلىق ئانتىبىئوتىكلارغا باشلىدى.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
2 ياشلىق بىر قىز ئالدىنقى كۈنى يۈزىدە ھاشارات چىشلىۋالغاندىن كېيىن ، پۈتۈن بەدىنىدە 48 سائەتتىن ئارتۇق تەرەققىي قىلغان دانىخورەك پەيدا بولدى. تەكشۈرۈش جەريانىدا ، ئۇ كىچىك دانىخورەكتىن تەركىب تاپقان كەڭ كۆلەمدە دانىخورەك پەيدا بولۇپ ، يېنىك سۈركىگەندە ، تېرىسىدە نىكولسكىي ئالامەتلىرى كۆرۈلگەن. دانىخورەك ئۇنىڭ شىللىق پەردىلىرىگە تەسىر قىلىدىغان ئالامەتلەر يوق. ئۇنىڭ قېنىدىكى سىناقتا ھېچقانداق يۇقۇملىنىش ئالامەتلىرى كۆرۈلمىگەن.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
بۇ يىغىندى كېسەللىكى S. aureus تەرىپىدىن قويۇپ بېرىلىدىغان ئېپىدېرمولىتلىق ئېكوتوكسىن (exfoliatin) A ۋە B تەرىپىدىن پەيدا بولىدۇ. بالىلاردىكى staphylococcal scalded skin syndrome نىڭ ئالدىن بېشارىتى ناھايىتى ياخشى بولۇپ ، داۋالاشنىڭ 10 كۈن ئىچىدە تولۇق ئېنىقلىقى بار ، كۆرۈنەرلىك داغ يوق. قانداقلا بولمىسۇن ، staphylococcal scalded skin syndrome چوقۇم ياخشى بولمىغان ئالدىن پەرەزنى ئېلىپ كېلىدىغان زەھەرلىك يۇقۇملۇق نېكرولىزدىن ئېھتىيات بىلەن پەرقلىنىشى كېرەك.
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#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)